Protein Modification Reagents
Medchemexpress LLC DSPE-PEG6-Mal | 95.0% | 1163.50 | 100 MG
DSPE-PEG6-Mal is a versatile reagent used in various biochemical and biomedical applications. It is commonly employed in drug delivery systems, particularly for modifying liposomes and nanoparticles to improve their circulation half-life and targeting capabilities. This compound facilitates bioconjugation reactions due to its maleimide group, which readily reacts with thiol-containing molecules.
- Facilitates bioconjugation reactions
- Used for surface modification of nanoparticles
- Enhances drug delivery systems
- Enables protein and peptide modification
Worthington Biochemical Corporation STEMXYME 2 COLLAGENASE 50MG
A specialized combination of Animal Origin-Free Clostridium histolyticum collagenase (Code: CLSAFB) and animal origin free Bacillus polymyxa neutral protease with a minimum of 250 CLS units and 2,000 caseinase units per mg dry weight. Designed for stem cell and other primary cell isolations and bioprocessing applications where introduction of potential animal derived pathogens must be prevented. 2593-92-3
Medchemexpress LLC Dbco-nhco-peg4-nh-boc | 1255942-12-1 | MFCD30730371 | >96.0% | 623.74 g/mol | C34H45N3O8 | 25 MG
Dbco-nhco-peg4-nh-boc is a DBCO-functionalized PEG4 linker used for copper-free click chemistry (SPAAC) in bioconjugation, antibody-drug conjugate assembly, and PROTAC synthesis.
- Enables copper-free click chemistry with azide-functionalized molecules.
- Suitable for antibody-drug conjugate and PROTAC linker synthesis.
- Boc-protected amine facilitates selective deprotection and further functionalization.
- Available in small laboratory quantities for research use.
- Stable when stored at recommended temperatures.
Medchemexpress LLC Pomalidomide-5'-peg8-c2-cooh | 2138440-78-3 | 98.2% | 697.73 | C32H47N3O14 | 10 MG
Pomalidomide-5'-PEG8-C2-COOH is an E3 ligase ligand-linker conjugate that links a pomalidomide E3 ligase ligand to an eight-unit polyethylene glycol (PEG8) spacer terminated with a two-carbon carboxylic acid. It is intended as a building block for PROTAC synthesis and other E3 ligase recruitment applications.
- Used as a building block for PROTAC synthesis and E3 ligase recruitment studies.
- Conjugate of pomalidomide and a PEG8 linker with a C2 carboxylic acid terminus.
- High purity: 98.2%.
- Molecular weight 697.73 g/mol; formula C32H47N3O14.
- Soluble in DMSO (100 mg/mL) and suitable in vivo formulations (≥2.5 mg/mL).
- Storage: pure form -20°C (3 years) or 4°C (2 years).
![Medchemexpress LLC Ethanol, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate) | 236754-49-7 | 98.5% | 417.48 g/mol | C17H27N3O7S | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000204060.png-250.jpg)
Medchemexpress LLC Ethanol, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate) | 236754-49-7 | 98.5% | 417.48 g/mol | C17H27N3O7S | 50 MG
Azide-PEG5-Tos is an azide-functionalized polyethylene glycol linker (PEG length = 5 units) with a tosylate leaving group, used for bioconjugation and assembly of antibody-drug conjugates. It enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) reactions to attach payloads to alkyne-bearing molecules.
- Contains an azide moiety for click chemistry conjugations.
- Peg5 spacer provides hydrophilicity and flexibility.
- Tosylate group serves as a reactive leaving group for functionalization.
- High purity suitable for research applications.
- Soluble in DMSO at ≥100 mg/mL for convenient stock solutions.
Sigma Aldrich Fine Chemicals Biosciences Trypsin from bovine pancreas | 9002-07-7 | MFCD00082094 | 1 g
Trypsin from bovine pancreas | Mol Wt: 23.8 kDa | 9002-07-7 | MFCD00082094 | 1 g
Medchemexpress LLC Dbco-peg2-val-cit-pab-mmae | 2845934-59-8 | 99.3% | 1569.92 g/mol | C84H120N12O17 | 25 MG
A cleavable ADC linker composed of a DBCO reactive handle, a PEG2 spacer, a cathepsin-cleavable valine-citrulline dipeptide with a para-aminobenzyl (PAB) self-immolative spacer, and the cytotoxic MMAE payload. Designed for conjugation via strain-promoted alkyne-azide cycloaddition (SPAAC) to form antibody-drug conjugates.
- High purity suitable for conjugation reactions.
- Cleavable val-cit dipeptide enables payload release in lysosomes.
- Dbco moiety supports copper-free click conjugation (SPAAC).
- Peg2 spacer improves solubility and linker flexibility.
- Available in small mg-scale quantities for synthesis and development.
Medchemexpress LLC Mal-PEG2-NH2 TFA | 660843-23-2 | 99.37% | 342.27 | 100 MG
Mal-PEG2-NH2 (TFA) is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are composed of two different ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Appearance: oil
- Color: light yellow to yellow
- Shipping: room temperature in continental US
- Storage: -20°C, stored under nitrogen, away from moisture
- Solubility (in vitro): DMSO: 100 mg/mL (292.17 mM; requires ultrasonic)
Gelest Inc Methoxytriethyleneoxypropyltrimethoxysilane | 132388-45-5 | MFCD09953872 | 10g
This item has a minimum qty of 3 per supplier requirements.
Methoxytriethyleneoxypropyltrimethoxysilane | MW: 326.46 | 132388-45-5 | MFCD09953872 | 10g
Mitegen PEG 6000, 50%(w/v), 250 ml, CAS# 25322-68-3
Use our stock solutions directly or as a component in solutions you create in your own lab. We prepare our stock solutions using high quality raw materials, ASTM Type 1 water, and sterile packaging. Our stock solutions are intended for Research and Development Use Only.